Article
Requirements for ATP binding and hydrolysis in RecA function in Escherichia coli.
Molecular microbiology - 1 Mar 2008
Renzette Nicholas, Sandler Steven J
Abstract excerpt
RecA is essential for recombination, DNA repair and SOS induction in Escherichia coli. ATP hydrolysis is known to be important for RecA's roles in recombination and DNA repair. In vitro reactions modelling SOS induction minimally require ssDNA and non-hydrolyzable ATP analogues. This predicts that ATP hydrolysis will not be required for SOS induction in vivo. The requirement of ATP binding and hydrolysis for SOS...
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