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Article

Physical and Functional Interactions between STAT5 and Runx Transcription Factors

22 Feb 2008

Abstract excerpt

The signal transducers and activators of transcription (STAT) and the Runt-related (Runx) are two of major transcription factor families that play essential roles in lymphocyte development. Although the interaction of Runx2 with STAT1 and STAT3 has been reported before, the interaction between STAT5 and Runx family proteins has not been characterized. In this study, we first showed that STAT5 physically interacts...

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PMID: 18296717
DOI: 10.1093/jb/mvn022

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