Article
Iron intake, oxidative stress-related genes (MnSOD and MPO) and prostate cancer risk in CARET cohort.
Carcinogenesis - 1 May 2008
Choi Ji-Yeob, Neuhouser Marian L, Barnett Matt J, Hong Chi-Chen, Kristal Alan R, Thornquist Mark D, King Irena B, Goodman Gary E, Ambrosone Christine B
Abstract excerpt
Iron overload may increase prostate cancer risk through stimulation of oxidative stress, and endogenous pro- and antioxidant capabilities, i.e. manganese superoxide dismutase (MnSOD) and myeloperoxidase (MPO), may modify these associations. We investigated this hypothesis in the Carotene and Retinol Efficacy Trial cohort in a nested case-control study. Although there was no association between iron intake and...
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