Article
Congenital exposure to Plasmodium falciparum antigens: prevalence and antigenic specificity of in utero-produced antimalarial immunoglobulin M antibodies.
Infection and immunity - 1 Mar 2003
Xi Guoling, Leke Rose G F, Thuita Lucy W, Zhou Ainong, Leke Robert J I, Mbu Robinson, Taylor Diane Wallace
Abstract excerpt
Congenital Plasmodium falciparum malaria in newborns is uncommon in sub-Saharan Africa. A significant number of infants, however, become infected or exposed to malarial antigens either in utero or at delivery and have the potential to produce antimalarial antibodies and memory cells before their first natural infection. In Yaounde, Cameroon, parasite-specific immunoglobulin M (IgM) was detected in 14% of cord...
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