Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IL-10 Suppresses Mast Cell IgE Receptor Expression and Signaling In Vitro and In Vivo

1 Mar 2008

Abstract excerpt

Mast cells are known for their roles in allergy, asthma, systemic anaphylaxis, and inflammatory disease. IL-10 can regulate inflammatory responses and may serve as a natural regulator of mast cell function. We examined the effects of IL-10 on in vitro-cultured mouse and human mast cells, and evaluated the effects of IL-10 on FcepsilonRI in vivo using mouse models. IgE receptor signaling events were also assessed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma and respiratory diseases
Share to Mast cells and histamine
Share to Urticaria and Related Conditions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18292506
DOI: 10.4049/jimmunol.180.5.2848

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IL-10 Suppresses Mast Cell IgE Receptor Expression and Signaling In Vitro and In VivoPMID 18292506Read ↗

IL-10–Induced miR-155 Targets SOCS1 To Enhance IgE-Mediated Mast Cell FunctionSemantic proximity Read ↗

Regulation of mast cell responses in health and disease.Semantic proximity Read ↗

FcεRIγ-ITAM Is Differentially Required for Mast Cell Function In VivoSemantic proximity Read ↗

FcεRI: A Master Regulator of Mast Cell FunctionsSemantic proximity Read ↗

Genome-wide gene expression profiling of human mast cells stimulated by IgE or FcεRI-aggregation reveals a complex network of genes involved in inflammatory responsesSemantic proximity Read ↗

Human TLR10 is an anti-inflammatory pattern-recognition receptor.Semantic proximity Read ↗

Deciphering the structure and function of FcεRI/mast cell axis in the regulation of allergy and anaphylaxis: a functional genomics paradigmSemantic proximity Read ↗

Mesenchymal stem cells overexpressing interleukin-10 prevented allergic airway inflammationSemantic proximity Read ↗

Widespread immunological functions of mast cells: fact or fiction?Semantic proximity Read ↗

Suppression of mast cell degranulation through a dual-targeting tandem IgE-IgG Fc domain biologic engineered to bind with high affinity to FcγRIIb.Semantic proximity Read ↗

Signaling molecules as therapeutic targets in allergic diseases.Semantic proximity Read ↗

MAST CELLS AS “TUNABLE” EFFECTOR AND IMMUNOREGULATORY CELLS: Recent AdvancesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.