Article
Prevalence of BRCA1 and BRCA2 mutations in breast cancer patients from Cuba.
Familial cancer - 1 Jan 2008
Rodriguez Rolando Comacho, Esperon Antonio Alejandro, Ropero Ramon, Rubio Maria Caridad, Rodriguez Ronald, Ortiz Rosa M, Anta Juan J Lence, de los Rios Mario, Carnesolta Deyanira, del Olivera Maria C, Vansam Somalia Stiu, Royer Robert, Akbari Mohammad R, Donenberg Talia, Narod Steven A
Abstract excerpt
The contribution of BRCA1 and BRCA2 to breast cancer incidence in Cuba has not yet been explored. In order to estimate the proportion of breast cancers due to BRCA1 and BRCA2 mutations in Cuba, and to identify possible Cuban founder mutations, we conducted a study of unselected breast cancer patients from Havana, Cuba. We enrolled 336 women with breast cancer from a large public hospital in the city. A family...
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