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Article

BRCA1 and BRCA2 mutations in breast cancer patients from Venezuela.

Biological research - 1 Jan 2012

Lara Karlena, Consigliere Nigmet, Pérez Jorge, Porco Antonietta

Abstract excerpt

A sample of 58 familial breast cancer patients from Venezuela were screened for germline mutations in the coding sequences and exon-intron boundaries of BRCA1 (MIM no. 113705) and BRCA2 (MIM no. 600185) genes by using conformation-sensitive gel electrophoresis. Ashkenazi Jewish founder mutations were not found in any of the samples. We identified 6 (10.3%) and 4 (6.9%) patients carrying germline mutations in...

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Source

Identifiers

PMID: 23096355
DOI: 10.4067/S0716-97602012000200003

Genes

BRCA2
BRCA1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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