Article
BRCA1 and BRCA2 mutations among ovarian cancer patients from Colombia.
Gynecologic oncology - 1 Feb 2012
Rodríguez Alexandra Ortiz, Llacuachaqui Marcia, Pardo Gonzalo Guevara, Royer Robert, Larson Garrett, Weitzel Jeffrey N, Narod Steven A
Abstract excerpt
OBJECTIVE: The contribution of BRCA1 and BRCA2 mutations to ovarian cancer in Colombia has not yet been explored. Five founder mutations have been identified in two previous studies of breast cancer patients in the Bogota region [1,2]. It is important that the frequency of mutations be established among unselected cases of ovarian cancer in order to estimate the genetic burden of this cancer in Colombia and to...
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