Article
The success of the genome-wide association approach: a brief story of a long struggle.
European journal of human genetics : EJHG - 1 May 2008
Seng Ku Chee, Seng Chia Kee
Abstract excerpt
The genome-wide association approach has been the most powerful and efficient study design thus far in identifying genetic variants that are associated with complex human diseases. This approach became feasible as the result of several key advancements in genetic knowledge, genotyping technologies, statistical analysis algorithms and the availability of large collections of cases and controls. With all these...
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