Article
Nucleotide substitution rate of mammalian mitochondrial genomes.
Journal of molecular evolution - 1 Apr 1999
Pesole G, Gissi C, De Chirico A, Saccone C
Abstract excerpt
We present here for the first time a comprehensive study based on the analysis of closely related organisms to provide an accurate determination of the nucleotide substitution rate in mammalian mitochondrial genomes. This study examines the evolutionary pattern of the different functional mtDNA regions as accurately as possible on the grounds of available data, revealing some important "genomic laws." The main...
Topics
- Animals
- DNA, Mitochondrial
- Evolution, Molecular
- Genome
- Humans
- Mammals
- Mutation
- RNA, Ribosomal
- RNA, Transfer