Article
Survivin and laryngeal carcinoma prognosis: nuclear localization and expression of splice variants.
Histopathology - 1 Aug 2012
Marioni Gino, Agostini Marco, Bedin Chiara, Blandamura Stella, Stellini Edoardo, Favero Giovanni, Lionello Marco, Giacomelli Luciano, Burti Silvia, D'Angelo Edoardo, Nitti Donato, Staffieri Alberto, De Filippis Cosimo
Abstract excerpt
AIMS: Aberrant survivin expression in cancer cells has been associated with tumour progression, radiation/drug resistance and shorter patient survival. The aim of the present study was to investigate survivin expression in laryngeal carcinoma (LSCC) tissue and - for the first time at this site - the expression of survivin splice variants. P53 was also studied. METHODS AND RESULTS: Survivin and p53 expression was...
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