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Novel AAV serotypes for improved ocular gene transfer

18 Feb 2008

Abstract excerpt

Some of the most successful gene therapy results have been obtained using recombinant viral vectors to treat animal models of inherited and acquired ocular diseases. Clinical trials using adenovirus vector systems have been initiated for two ocular diseases. Adeno-associated viruses (AAVs) represent an attractive alternative to adenoviral vector systems as they enable stable and long-term expression and can...

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PMID: 18278824
DOI: 10.1002/jgm.1126

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