Article
Molecular mechanism and classification of von Willebrand disease.
Thrombosis and haemostasis - 1 Jul 1995
Sadler J E, Matsushita T, Dong Z, Tuley E A, Westfield L A
Abstract excerpt
The characterization of mutations in von Willebrand disease provides useful insight into the synthesis, structure, and function of von Willebrand factor. This growing body of information has prompted a reclassification of vWD types that is intended to reflect distinct pathophysiologic mechanisms. Despite this apparent progress, many aspects of vWF biology and pathophysiology remain poorly understood. These...
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