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Article

IL-8 gene expression and production in human peripheral blood lymphocyte subsets

1 Jun 1991

Abstract excerpt

We have investigated IL-8 mRNA expression and IL-8 production in highly purified subsets of peripheral blood lymphocytes. T cells stimulated with PHA, ionomycin, or PMA alone failed to express IL-8 mRNA. However T cells stimulated with a combination of PMA and ionomycin or PMA and PHA expressed IL-8 mRNA in a PMA dose-dependent manner and maximally after 3 to 6 h of culture. Induction of IL-8 mRNA appeared to be...

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Identifiers

PMID: 1827816
DOI: 10.4049/jimmunol.146.11.3815

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