Article
Cord blood islet autoantibodies and seasonal association with the type 1 diabetes high-risk genotype.
Journal of perinatology : official journal of the California Perinatal Association - 1 Mar 2008
Lynch K F, Lernmark B, Merlo J, Cilio C M, Ivarsson S-A, Lernmark A
Abstract excerpt
OBJECTIVE: Human leukocyte antigen DQ (HLA-DQ) genetic factors and islet autoantibodies are strongly associated with type 1 diabetes (T1D) and are currently used to predict T1D. This study examined whether islet autoantibodies in the cord blood of newborns to nondiabetic mothers were associated with the (T1D) high-risk genotype HLA-DQ2/8, gestational infections or both. STUDY DESIGN: Cord blood samples were taken...
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