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Article

A novel, evolutionarily conserved enhancer of cone photoreceptor-specific expression.

The Journal of biological chemistry - 18 Apr 2008

Smyth Vincent A, Di Lorenzo David, Kennedy Breandán N

Abstract excerpt

The alpha subunit of cone transducin (TalphaC) is expressed exclusively in cone photoreceptors of the eye and pineal. TalphaCisakey phototransduction protein, and inherited mutations in TalphaC cause total color blindness in humans. We use transgenic zebrafish to identify and characterize cone photoreceptor regulatory element 1 (CPRE-1) a novel 20-bp enhancer element in the TalphaC promoter (TalphaCP). CPRE-1 is...

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Identifiers

PMID: 18272521
DOI: 10.1074/jbc.M710454200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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