Article
Adverse adipose phenotype and hyperinsulinemia in gravid mice deficient in placental growth factor.
Endocrinology - 1 May 2008
Hemmeryckx Bianca, van Bree Rita, Van Hoef Berthe, Vercruysse Lisbeth, Lijnen H Roger, Verhaeghe Johan
Abstract excerpt
Pregnancy-induced metabolic changes are regulated by signals from an expanded adipose organ. Placental growth factor (PlGF), acting through vascular endothelial growth factor receptor-1, may be among those signals. There is a steep rise in circulating PlGF during normal pregnancy, which is repres...
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