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Article

Circ_0081343 promotes autophagy and alleviates pyroptosis via PI3 K/AKT/HIF-1α axis in hypoxia-induced fetal growth restriction of mice

6 May 2025

Abstract excerpt

OBJECTIVE: Fetal growth restriction (FGR) is a serious pregnancy complication associated with an increased risk of perinatal morbidity and mortality. Notably, circular RNAs (circRNAs) significantly influence physiological development and disease pathogenesis. We reported previously that lower circ_0081343 expression is associated with placental trophoblast dysfunction. However, only a few studies have reported...

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PMID: 40353255
DOI: 10.1080/19768354.2025.2498932

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