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Article

A progesterone-brown fat axis is involved in regulating fetal growth.

Scientific reports - 6 Sept 2017

McIlvride Saraid, Mushtaq Aleena, Papacleovoulou Georgia, Hurling Chloe, Steel Jennifer, Jansen Eugène, Abu-Hayyeh Shadi, Williamson Catherine

Abstract excerpt

Pregnancy is associated with profound maternal metabolic changes, necessary for the growth and development of the fetus, mediated by reproductive signals acting on metabolic organs. However, the role of brown adipose tissue (BAT) in regulating gestational metabolism is unknown. We show that BAT phenotype is lost in murine pregnancy, while there is a gain of white adipose tissue (WAT)-like features. This is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28878263
DOI: 10.1038/s41598-017-10979-7
PMCID: PMC5587669

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