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Article

Influence of alternative thresholds for initiating HIV treatment on quality-adjusted life expectancy: a decision model.

Annals of internal medicine - 5 Feb 2008

Braithwaite R Scott, Roberts Mark S, Chang Chung Chou H, Goetz Matthew Bidwell, Gibert Cynthia L, Rodriguez-Barradas Maria C, Shechter Steven, Schaefer Andrew, Nucifora Kimberly, Koppenhaver Robert, Justice Amy C

Abstract excerpt

BACKGROUND: The optimal threshold for initiating HIV treatment is unclear. OBJECTIVE: To compare different thresholds for initiating HIV treatment. DESIGN: A validated computer simulation was used to weigh important harms from earlier initiation of antiretroviral therapy (toxicity, side effects, and resistance accumulation) against important benefits (decreased HIV-related mortality). DATA SOURCES: Veterans Aging...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18252681
DOI: 10.7326/0003-4819-148-3-200802050-00004
PMCID: PMC3124094

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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