Article
Characterization of LORF11, a unique gene common to the three Marek's disease virus serotypes.
Avian diseases - 1 Dec 2007
Lee Lucy F, Silva Robert F, Cui Xiaoping, Zhang Huanmin, Heidari Mohammad, Reddy Sanjay M
Abstract excerpt
The unique open reading frame 11 (LORF11) of Marek's disease virus (MDV) is present in all three serotypes of MDV and is located in the unique long region of the MDV genome. In the serotype 1 Md5 genome, LORF11 comprises 2711 nucleotides and encodes a predicted protein of 903 amino acids. In order to study the biological function of LORF11 we deleted it from the MDV cosmid A6 by using the RecA-assisted...
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