Article
Enhanced type X collagen expression in the extruded nucleus pulposus of the chondrodystrophoid dog.
The Journal of veterinary medical science - 1 Jan 2008
Itoh Hisanori, Asou Yoshinori, Hara Yasushi, Haro Hirotaka, Shinomiya Kenichi, Tagawa Masahiro
Abstract excerpt
The causes of early degeneration and calcification of the nucleus pulposus in the chondrodystrophoid dog are poorly understood, and the underlying molecular mechanism of this process has not yet been clearly defined. Type X collagen is one of the key molecules in endochondral bone growth and development, especially matrix calcification. The relationship between type X collagen and disc degeneration and...
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