Article
Regulatory activity of activated murine peripheral CD4+CD25- T cells: a possible mechanism of feedback regulation on adaptive immunity.
Scandinavian journal of immunology - 1 Nov 2006
Lu Y, Xu W, Zhou Y, Lv P, Gao X-M
Abstract excerpt
This study was undertaken to investigate the possibility that peripheral CD4+CD25- T cells, once fully activated, transiently obtain suppressive function against other T cells. CD4+CD25- T cells, isolated from splenocytes of BALB/c mice, were stimulated with anti-CD3 MoAb in the presence of feeder cells for 72 h. The activated CD4+ T cells (T(act)) thus obtained were able to inhibit the activation and...
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