Article
A replicated molecular genetic basis for subtyping antisocial behavior in children with attention-deficit/hyperactivity disorder.
Archives of general psychiatry - 1 Feb 2008
Caspi Avshalom, Langley Kate, Milne Barry, Moffitt Terrie E, O'Donovan Michael, Owen Michael J, Polo Tomas Monica, Poulton Richie, Rutter Michael, Taylor Alan, Williams Benjamin, Thapar Anita
Abstract excerpt
CONTEXT: Attention-deficit/hyperactivity disorder (ADHD) is a heterogeneous neurodevelopmental disorder that in some cases is accompanied by antisocial behavior. OBJECTIVE: To test if variations in the catechol O-methyltransferase gene (COMT) would prove useful in identifying the subset of children with ADHD who exhibit antisocial behavior. DESIGN: Three independent samples composed of 1 clinical sample of ADHD...
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