COMT and DAT1 genes are associated with hyperactivity and inattention traits in the 1993 Pelotas Birth Cohort: evidence of sex-specific combined effect.

doi:10.1503/jpn.150270

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Article

COMT and DAT1 genes are associated with hyperactivity and inattention traits in the 1993 Pelotas Birth Cohort: evidence of sex-specific combined effect.

Journal of psychiatry & neuroscience : JPN - 1 Oct 2016

Akutagava-Martins Glaucia C, Salatino-Oliveira Angelica, Kieling Christian, Genro Julia P, Polanczyk Guilherme V, Anselmi Luciana, Menezes Ana M B, Gonçalves Helen, Wehrmeister Fernando C, Barros Fernando C, Callegari-Jacques Sidia M, Rohde Luis A, Hutz Mara H

Abstract excerpt

BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) symptoms are dimensionally distributed in the population. This study aimed to assess the role of the catechol-O-methyltransferase (COMT) and of the dopamine transporter (DAT1) genes on ADHD symptoms in the general population. METHODS: We investigated 4101 individuals from the 1993 Pelotas Birth Cohort Study using the parent version of the Strengths and...

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PMID: 27327562
DOI: 10.1503/jpn.150270
PMCID: PMC5082511

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COMT

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