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Article

Genotype link with extreme antisocial behavior: the contribution of cognitive pathways.

Archives of general psychiatry - 1 Dec 2010

Langley Kate, Heron Jon, O'Donovan Michael C, Owen Michael J, Thapar Anita

Abstract excerpt

CONTEXT: As genes associated with common disorders are increasingly identified, we need to progress from observing associations to identifying risk pathways. The high-activity COMT genotype, in the presence of attention-deficit/hyperactivity disorder (ADHD), has previously been shown to be associated with extreme antisocial behavior. The same genotype has also been implicated in affecting cognitive function in...

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Source

Identifiers

PMID: 21135332
DOI: 10.1001/archgenpsychiatry.2010.163

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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