Article
Contribution of capsular and clonal types and beta-lactam resistance to the severity of experimental pneumococcal meningitis.
Microbes and infection - 1 Feb 2008
Ribes Sandra, Taberner Ferran, Cabellos Carmen, Tubau Fe, Ardanuy Carmen, Gerber Joachim, Liñares Josefina, Nau Roland, Gudiol Francesc
Abstract excerpt
We used a rabbit model to assess the effects of capsular serotype, genetic background and beta-lactam resistance on the course and severity of experimental meningitis. Meningitis was induced by five pneumococcal strains belonging to five different clones with known invasive potential: two serotype 3 strains (ST260(3) and Netherlands(3)-31 clones) and three serotype 23F strains with different beta-lactam...
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