Article
[Relationship between virulence and resistance to antibiotics in pneumococci. Contribution of experimental data obtained in an animal model].
Pathologie-biologie - 1 Dec 1991
Bédos J P, Rolin O, Bouanchaud D H, Pocidalo J J
Abstract excerpt
Epidemiologic data show that the organ affinity of Streptococcus pneumoniae varies across serotypes. As a result of this heterogeneous distribution, exposure to antimicrobials is greater for serotypes 6, 14, 19 and 23. Most strains with resistance to antimicrobials are found among these four serotypes. Virulence of the various serotypes of pneumococci varies with adhesion, enzyme secretion, and resistance to...
Topics
- Animals
- Anti-Bacterial Agents
- Disease Models, Animal
- Drug Resistance, Microbial
- Female
- Macrolides
- Male
- Mice
- Penicillin Resistance
- Penicillins
- Phenotype
