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Article

Delayed cell death associated with mitotic catastrophe in γ-irradiated stem-like glioma cells

10 Jun 2011

Abstract excerpt

BACKGROUND AND PURPOSE: Stem-like tumor cells are regarded as highly resistant to ionizing radiation (IR). Previous studies have focused on apoptosis early after irradiation, and the apoptosis resistance observed has been attributed to reduced DNA damage or enhanced DNA repair compared to non-stem tumor cells. Here, early and late radioresponse of patient-derived stem-like glioma cells (SLGCs) and differentiated...

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PMID: 21663643
DOI: 10.1186/1748-717x-6-71

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