Article
Analysis of nuclear and mitochondrial genes in patients with pseudoexfoliation glaucoma.
Molecular vision - 10 Jan 2008
Abu-Amero Khaled K, Bosley Thomas M, Morales Jose
Abstract excerpt
PURPOSE: Pseudoexfoliation glaucoma (PEG) is the most prevalent secondary open angle glaucoma occurring worldwide. The search for a genetic cause in PEG has been largely unsuccessful despite evidence of hereditary transmission. METHODS: The nuclear genes MYOC, OPTN, WDR36, CYP1B1, OPA1, and OPA3 were sequenced in patients with PEG. The entire mitochondrial DNA (mtDNA) coding region was also sequenced, relative...
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