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Article

A novel screening method for cell wall mutants in Aspergillus niger identifies UDP-galactopyranose mutase as an important protein in fungal cell wall biosynthesis.

Genetics - 1 Feb 2008

Damveld Robbert A, Franken Angelique, Arentshorst Mark, Punt Peter J, Klis Frans M, van den Hondel Cees A M J J, Ram Arthur F J

Abstract excerpt

To identify cell wall biosynthetic genes in filamentous fungi and thus potential targets for the discovery of new antifungals, we developed a novel screening method for cell wall mutants. It is based on our earlier observation that the Aspergillus niger agsA gene, which encodes a putative alpha-glucan synthase, is strongly induced in response to cell wall stress. By placing the agsA promoter region in front of a...

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Identifiers

PMID: 18245853
DOI: 10.1534/genetics.107.073148
PMCID: PMC2248356

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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