Article
Blood-derived smooth muscle cells as a target for gene delivery.
Journal of vascular surgery - 1 Feb 2008
Yang Zhe, Shao Hongwei, Tan Yaohong, Eton Darwin, Yu Hong
Abstract excerpt
OBJECTIVE: To examine the feasibility of using blood-derived smooth muscle cells (BD-SMCs) as a target for to deliver therapeutic proteins. MATERIALS AND METHODS: Mononuclear cells (MNC) were isolated from peripheral blood. The outgrowth colonies from MNC culture were differentiated into BD-SMCs in media containing platelet-derived growth factor BB. Phenotypic characterization of BD-SMCs was assessed by...
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