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Article

Computational and experimental studies on the catalytic mechanism of biliverdin-IXbeta reductase.

The Biochemical journal - 1 May 2008

Smith Liam J, Browne Seamus, Mulholland Adrian J, Mantle Timothy J

Abstract excerpt

BVR-B (biliverdin-IXbeta reductase) also known as FR (flavin reductase) is a promiscuous enzyme catalysing the pyridine-nucleotide-dependent reduction of a variety of flavins, biliverdins, PQQ (pyrroloquinoline quinone) and ferric ion. Mechanistically it is a good model for BVR-A (biliverdin-IXalpha reductase), a potential pharmacological target for neonatal jaundice and also a potential target for adjunct...

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PMID: 18241201
DOI: 10.1042/BJ20071495

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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