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Article

Structural basis for hydration dynamics in radical stabilization of bilin reductase mutants.

Biochemistry - 27 Jul 2010

Kohler Amanda C, Gae David D, Richley Michael A, Stoll Stefan, Gunn Alexander, Lim Sunghyuk, Martin Shelley S, Doukov Tzanko I, Britt R David, Ames James B, Lagarias J Clark, Fisher Andrew J

Abstract excerpt

Heme-derived linear tetrapyrroles (phytobilins) in phycobiliproteins and phytochromes perform critical light-harvesting and light-sensing roles in oxygenic photosynthetic organisms. A key enzyme in their biogenesis, phycocyanobilin:ferredoxin oxidoreductase (PcyA), catalyzes the overall four-electron reduction of biliverdin IXalpha to phycocyanobilin--the common chromophore precursor for both classes of...

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Identifiers

PMID: 20557110
DOI: 10.1021/bi100728q
PMCID: PMC2914091

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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