Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differentiated Fibroblastic Progenies of Human Embryonic Stem Cells for Toxicology Screening

3 Feb 2008

Abstract excerpt

Immortalized cell lines and live animal models are commonly used for cytotoxicity screening of biomedical devices and materials. However, these assays poorly reflect human physiology and have numerous other disadvantages. An alternative may be to utilize differentiated fibroblastic progenies of human embryonic stem cells (hESC) for in vitro toxicology screening. These were generated through random spontaneous...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3D Printing in Biomedical Research
Share to Pluripotent Stem Cells Research
Share to Tissue Engineering and Regenerative Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18241121
DOI: 10.1089/clo.2007.0049

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differentiated Fibroblastic Progenies of Human Embryonic Stem Cells for Toxicology ScreeningPMID 18241121Read ↗

Standardization of pluripotent stem cell cultures for toxicity testingSemantic proximity Read ↗

Evaluation of human embryonic stem cells and their differentiated fibroblastic progenies as cellular models for in vitro genotoxicity screeningSemantic proximity Read ↗

Stem Cells in Toxicology: Fundamental Biology and Practical ConsiderationsSemantic proximity Read ↗

Prospects and Frontiers of Stem Cell ToxicologySemantic proximity Read ↗

Present state and future perspectives of using pluripotent stem cells in toxicology researchSemantic proximity Read ↗

Human induced pluripotent stem cell-derived hepatocytes for toxicology testingSemantic proximity Read ↗

Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes as an in vitro model in toxicology: strengths and weaknesses for hazard identification and risk characterizationSemantic proximity Read ↗

The biological and ethical basis of the use of human embryonic stem cells for in vitro test systems or cell therapySemantic proximity Read ↗

Human embryonic stem cell technologies and drug discoverySemantic proximity Read ↗

Evaluation of the use of human Mesenchymal Stem Cells for acute toxicity testsSemantic proximity Read ↗

Toxicological applications of human induced pluripotent stem cell-derived hepatocyte-like cells: an updated reviewSemantic proximity Read ↗

Human mesenchymal stem cells as a novel platform for simultaneous evaluation of cytotoxicity and genotoxicity of pharmaceuticalsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.