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Stem Cells in Toxicology: Fundamental Biology and Practical Considerations

16 Dec 2010

Abstract excerpt

This "Commentary" has examined the use of human stem cells for detection of toxicities of physical, chemical, and biological toxins/toxicants in response to the challenge posed by the NRC Report, "Toxicity Testing in the 21st Century: A vision and Strategy." Before widespread application of the use of human embryonic, pluripotent, "iPS," or adult stem cells be considered, the basic characterization of stem cell...

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PMID: 21163910
DOI: 10.1093/toxsci/kfq370

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