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Article

Scanning electron microscopic analysis of intramyocellular lipid droplets in an animal model of type 2 diabetes.

Obesity (Silver Spring, Md.) - 1 Mar 2008

Fraenkel Merav, Weiss Ram, Leizerman Ilit, Anaby Debbie, Golomb Eliahu, Leibowitz Gil, Kaiser Nurit

Abstract excerpt

OBJECTIVE: To evaluate the accumulation pattern of intramyocellular lipids (IMCLs) in striated muscle during the development and progression of diabetes, using a novel scanning electron microscopic method. METHODS AND PROCEDURES: Hyperglycemia was induced by feeding diabetes-prone (DP) Psammomys obesus a high-energy (HE) diet. Lipid accumulation within gastrocnemius muscle fibers was assessed in formalin-fixed...

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PMID: 18239599
DOI: 10.1038/oby.2007.105

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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