Article
Characterization of ghrelin in pedigreed baboons: evidence for heritability and pleiotropy.
Obesity (Silver Spring, Md.) - 1 Apr 2008
Voruganti V Saroja, Tejero M Elizabeth, Proffitt J Michael, Cole Shelley A, Cox Laura A, Mahaney Michael C, Rogers Jeffery A, Freeland-Graves Jeanne H, Comuzzie Anthony G
Abstract excerpt
BACKGROUND: Ghrelin is an orexigenic hormone that is produced primarily in the stomach, and stimulates food intake via its receptors situated in the hypothalamus. OBJECTIVE: The purpose of this study was to characterize baboon ghrelin cDNA and investigate the genetic influence on the variation in plasma ghrelin levels in baboons. METHODS AND PROCEDURES: The sample consisted of 376 baboons (263 females, 113 males)...
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