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Article

Nuclear myosin I acts in concert with polymeric actin to drive RNA polymerase I transcription.

Genes & development - 1 Feb 2008

Ye Jing, Zhao Jian, Hoffmann-Rohrer Urs, Grummt Ingrid

Abstract excerpt

Actin is associated with all three nuclear RNA polymerases and acts in concert with nuclear myosin I (NM1) to drive transcription. Practically nothing is known regarding the state of actin and the functional interplay of actin and NM1 in transcription. Here we show that actin and NM1 act in concert to promote RNA polymerase I (Pol I) transcription. Drugs that prevent actin polymerization or inhibit myosin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18230700
DOI: 10.1101/gad.455908
PMCID: PMC2216692

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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