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Article

Reference genes for normalization of gene expression studies in human osteoarthritic articular cartilage

29 Jan 2008

Abstract excerpt

BACKGROUND: Assessment of gene expression is an important component of osteoarthritis (OA) research, greatly improved by the development of quantitative real-time PCR (qPCR). This technique requires normalization for precise results, yet no suitable reference genes have been identified in human articular cartilage. We have examined ten well-known reference genes to determine the most adequate for this...

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PMID: 18226276
DOI: 10.1186/1471-2199-9-17

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