Article
The interleukin-1 beta gene polymorphism +3953 C/T is not associated with risk for oral cancer.
Anticancer research - 1 Jan 2000
Vairaktaris Eleftherios, Serefoglou Zoe, Yapijakis Christos, Stathopoulos Panagiotis, Vassiliou Stavros, Derka Spyridoula, Nkenke Emeka, Vylliotis Antonis, Ragos Vasilios, Neukam Friedrich W, Patsouris Efstratios
Abstract excerpt
BACKGROUND: Elevated serum levels of interleukin-1 beta (IL-1beta) have been previously observed in patients with oral cancer. Considering the demonstrated effect of other interleukins to the development of oral cancer, this study investigated whether the +3953 C/Tpolymorphism in the IL-1beta gene is associated with this malignancy. PATIENTS AND METHODS: The +3953 C/T polymorphism was examined in DNA samples of...
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