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Article

IL-1β Regulates FHL2 and Other Cytoskeleton-Related Genes in Human Chondrocytes

1 Mar 2008

Abstract excerpt

In osteoarthritis (OA), cartilage destruction is associated not only with an imbalance of anabolic and catabolic processes but also with alterations of the cytoskeletal organization in chondrocytes, although their pathogenetic origin is largely unknown so far. Therefore, we have studied possible effects of the proinflammatory cytokine IL-1beta on components of the cytoskeleton in OA chondrocytes on gene...

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PMID: 18224250
DOI: 10.2119/2007-00118.joos

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