Article
Elevated serum levels of intercellular adhesion molecule ICAM-1 in Pseudoxanthoma elasticum.
Clinica chimica acta; international journal of clinical chemistry - 1 Aug 2008
Hendig Doris, Adam Alexandra, Zarbock Ralf, Szliska Christiane, Kleesiek Knut, Götting Christian
Abstract excerpt
BACKGROUND: Pseudoxanthoma elasticum (PXE, OMIM 177850 and 264800) is a rare heritable disorder predominantly affecting the skin, the eyes and the vascular system. The disease is caused by mutations in the ABCC6 gene and is characterized by calcification and extracellular matrix remodeling, including alterations of the vessel walls. Here, we investigated the cell adhesion molecules ICAM-1 in PXE patients....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.