Article
No association between common Gly972Arg variant of the insulin receptor substrate-1 and polycystic ovary syndrome in Southern Chilean women.
Clinica chimica acta; international journal of clinical chemistry - 1 Apr 2008
Valdés Patricio, Cerda Alvaro, Barrenechea Cristobal, Kehr Marlene, Soto Carolina, Salazar Luis A
Abstract excerpt
BACKGROUND: Previously studies have indicated that the insulin receptor substrate-1 (IRS-1) Gly972Arg (G972R) polymorphism is associated with polycystic ovary syndrome (PCOS). We examined the possible association between G972R common variant of the IRS-1 gene and PCOS in Southern Chilean women with PCOS and controls. METHODS: A total of 50 women with PCOS (29.1+/-8.1 yr) and 75 healthy women (29.3+/-9.3 yr) were...
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