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Article

Translational control plays a prominent role in the hepatocytic differentiation of HepaRG liver progenitor cells

25 Jan 2008

Abstract excerpt

BACKGROUND: We investigated the molecular events associated with the differentiation of liver progenitor cells into functional and polarized hepatocytes, using human HepaRG cells that display potent hepatocytic differentiation-inducible properties and share some features with liver progenitor cells. RESULTS: Profiling of total and of polysome-bound transcripts isolated from HepaRG cells undergoing hepatocytic...

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PMID: 18221535
DOI: 10.1186/gb-2008-9-1-r19

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