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Differentiation therapy: Unlocking phenotypic plasticity of hepatocellular carcinoma

17 Oct 2022

Abstract excerpt

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors. The current treatment of HCC mainly includes surgery, chemotherapy, and liver transplantation. HCC differentiation therapy aims to restore tumor cells' normal liver characteristics and unlock their phenotypic plasticity. Understanding the molecular and signaling pathways that control HCC differentiation can help identify new targets for...

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Cancer Mechanisms and Therapy
Liver physiology and pathology
Pancreatic function and diabetes

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36257532
DOI: 10.1016/j.critrevonc.2022.103854

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