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Induced Pluripotent Stem Cells as a Model for Accelerated Patient- and Disease-specific Drug Discovery

27 Jan 2010

Abstract excerpt

Human induced pluripotent stem (iPS) cells hold great promise for therapy of a number of degenerative diseases such as ischemic heart failure, Parkinson's disease, Alzheimer's disease, diabetes mellitus, sickle cell anemia and Huntington disease. They also have the potential to accelerate drug discovery in 3 ways. The first involves the delineation of chemical components for efficient reprogramming of patient's...

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PMID: 20088756
DOI: 10.2174/092986710790514480

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