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Article

Biostatistical aspects of genome-wide association studies.

Biometrical journal. Biometrische Zeitschrift - 1 Feb 2008

Ziegler Andreas, König Inke R, Thompson John R

Abstract excerpt

To search the entire human genome for association is a novel and promising approach to unravelling the genetic basis of complex genetic diseases. In these genome-wide association studies (GWAs), several hundreds of thousands of single nucleotide polymorphisms (SNPs) are analyzed at the same time, posing substantial biostatistical and computational challenges. In this paper, we discuss a number of biostatistical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genome, Human

Share to Oligonucleotide Array Sequence Analysis

Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 18217698
DOI: 10.1002/bimj.200710398

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