Article
Thrombin generation in first-degree relatives of patients with venous thromboembolism who have factor V Leiden. A pilot study.
Thrombosis and haemostasis - 1 Jan 2008
Couturaud Francis, Duchemin Jérôme, Leroyer Christophe, Delahousse Bénédicte, Abgrall Jean François, Mottier Dominique
Abstract excerpt
The thrombin generation test appears to be a highly sensitive and specific test in the detection of thrombophilia in patients with venous thromboembolism. We aimed to determine the accuracy of the thrombin generation test to detect factor V Leiden and/or other prothrombotic states in first-degree relatives of patients with venous thromboembolism and factor V Leiden. Sixty-two first-degree relatives of 21 index...
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