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Article

Forced myocardin expression enhances the therapeutic effect of human mesenchymal stem cells after transplantation in ischemic mouse hearts.

Stem cells (Dayton, Ohio) - 1 Apr 2008

Grauss Robert W, van Tuyn John, Steendijk Paul, Winter Elizabeth M, Pijnappels Daniël A, Hogers Bianca, Gittenberger-De Groot Adriana C, van der Geest Rob, van der Laarse Arnold, de Vries Antoine A F, Schalij Martin J, Atsma Douwe E

Abstract excerpt

Human mesenchymal stem cells (hMSCs) have only a limited differentiation potential toward cardiomyocytes. Forced expression of the cardiomyogenic transcription factor myocardin may stimulate hMSCs to acquire a cardiomyogenic phenotype, thereby improving their possible therapeutic potential. hMSCs were transduced with green fluorescent protein (GFP) and myocardin (hMSC(myoc)) or GFP and empty vector (hMSC). After...

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Identifiers

PMID: 18203678
DOI: 10.1634/stemcells.2007-0523

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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